Individuals with suspected COVID-19 symptoms (n=202) were tested using nasopharyngeal RT-qPCR. All individuals underwent corneal esthesiometry measurements using the Cochet-Bonnet esthesiometer during their first visit; 50 participants underwent an additional measurement at a mean interval of 32.5 (17.8) days. COVID-19 was confirmed in 101 subjects (50%) using nasopharyngeal PCR. The mean time from symptom onset to disease diagnosis and corneal esthesiometry was 4.2 (2.1) days. Mean corneal esthesiometry findings based on the positive and negative PCR status indicated no statistical difference. This study demonstrated that COVID-19 had no effect on corneal esthesiometry in individuals with acute-phase COVID-19.
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Contributors LBT contributed to data collection and wrote the paper. DdFS contributed to data collection and contibuted data/analysis tools. FH contributed to data/analysis tools and performed the analysis. DDC performed the analysis. ALH-L contributed to data/analysis tools. LBS contributed to data/analysis tools. NCJB conceived and designed the analysis; and contributed to data/analysis tools. DDF conceived and designed the analysis; and contributed to data/analysis tools. LAdO conceived and designed the analysis and helped to wrote the paper.
Funding This study was funded by Coordination for the Improvement of Higher Education Personnel (CAPES), Ministry of Education, Brazil and the Federal University of São Paulo (No grant number).
Disclaimer The sponsors or funding organisations had no role in the design or conduct of this research.
Competing interests None declared.
Provenance and peer review Commissioned; internally peer reviewed.