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The role of the lens in early refractive development: evidence from a large cohort of Chinese children (see page 1627)
The endpoint of early refractive development was found to be mild hyperopia rather than emmetropia. Achievement and maintenance of the mild hyperopic status were largely determined by a push-back mechanism between the axial elongation and lens power loss.
Influencing factors on effective lens position in patients with Marfan syndrome and ectopia lentis (see page 1634)
The effective lens position in Marfan patients was influenced by the IOL implantation procedure and varied among patients with different ocular parameters. The SRK/T formula performed best in Marfan syndrome.
Relapse in ocular tuberculosis: relapse rate, risk factors and clinical management in a non-endemic country (see page 1642)
In long-term follow-up, one-third of ocular tuberculosis cases experienced relapse. Patients who had persistent inflammation at 6 months after the initial uveitis treatment showed a higher risk of relapse. Relapse episodes responded well to immunosuppressant.
Posner-Schlossman syndrome European study group: study protocol and baseline patients characteristics of a multicentre study (see page 1652)
The study retrospectively analysed a multicentre dataset of patients with Posner-Schlossman syndrome. Among the 107 subjects, adult Caucasian men with mild anterior segment inflammation, preserved visual acuity but markedly increased IOP were the typical patients.
Long-term outcomes after acute primary angle closure: case series from Moorfields Eye Hospital, UK (see page 1659)
Patients affected by acute primary angle closure had good vision post-treatment, with delayed presentation correlating with increased treatment needs. Phacoemulsification as a treatment can improve visual results and decrease the necessity for additional intraocular pressure reduction treatment.
Enhancing the structure–function relationship in glaucoma using anatomical compensation of retinal nerve fibre layer (see page 1665)
Compensating for demographic and anatomical factors in retinal nerve fibre layer measurements enhances the correlation with visual field loss in glaucoma, improving the detection of structural and functional impairment.
Two-year outcomes of Xen 45 GEL stent implantation in patients with open-angle glaucoma: real-world data from the Fight Glaucoma Blindness Registry (see page 1672)
This study evaluated the efficacy and safety of the Xen 45 gel stent implant in the treatment of patients with open-angle glaucoma using real-world data from the Fight Glaucoma Blindness Registry. What the authors termed ‘complete success’ rate was IOP reduction >20% off glaucoma medications and requiring no further intervention within 2 years, and was found in only 26%.
Clinical features of patients with mutations in genes for nanophthalmos (see page 1679)
Angle closure glaucoma was frequently observed in nanophthalmos patients with variants in PRSS56, MFRP, MYRF, or TMEM98. Patients with autosomal recessive nanophthalmos showed more severe foveal hypoplasia while those with the dominant form had onset of glaucoma at an earlier age.
Detection of glaucoma progression on longitudinal series of en-face macular optical coherence tomography angiography images with a deep learning model (see page 1688)
A deep-learning model was designed for estimating glaucoma progression from a longitudinal series of optical coherence tomography angiography en face images. The model demonstrated good performance for estimating glaucoma progression.
Social history and glaucoma progression: the effect of body mass index, tobacco and alcohol consumption on the rates of structural change in patients with glaucoma (see page 1694)
In this retrospective cohort study, underweight patients with glaucoma presented significantly faster rates of structural loss over time. A history of tobacco or alcohol consumption was not associated with faster glaucoma progression.
Survival of medical treatment success in primary open-angle glaucoma and ocular hypertension (see page 1701)
In a large retrospective cohort, topical agents to prevent glaucoma progression maintained adequate control of intraocular pressure for a median of 1.6, 1.0, and 0.9 years following escalation from 0 to 1, 1-2, and 2-3 agents, respectively.
Associations of quantitative contrast sensitivity with vascular metrics on widefield swept-source OCT angiography across stages of diabetic retinopathy (see page 1708)
Diabetes-induced microvascular changes on OCT angiography are associated with larger changes in contrast sensitivity than in VA. Contrast sensitivity is affected earlier in diabetic retinopathy and was better than VA in discriminating across retinopathy stages.
Evaluation of systemic medications associated with diabetic retinopathy: a nested case–control study from the UK Biobank (see page 1716)
The use of short-acting insulins, medium-acting insulins and sulfonylureas is associated with increased odds of incident diabetic retinopathy, while fibrates and Cox-2 inhibitors are associated with decreased odds.
Metavision: a novel system for quantifying metamorphopsia in patients with myopic traction maculopathy (see page 1723)
The authors report a newly developed system (METAVISION) to quantify metamorphopsia in patients with myopic traction maculopathy (MTM). METAVISION can detect the location and severity of metamorphopsia and distinguish between regular and irregular metamorphopsia.
Improved accuracy of spectral-domain optical coherence tomography and optical coherence tomography angiography for monitoring myopic macular neovascularisation activity (see page 1729)
The combined use of spectral domain optical coherence tomography and optical coherence tomography angiography as first screening followed by selective use of fluorescence angiography is a reliable surveillance strategy for myopic macular neovascularisation activity.
Predicting the cognitive impairment with multimodal ophthalmic imaging and artificial neural network for community screening (see page 1737)
Based on analysis of multimodal ocular parameters obtained by a custom-built device, the authors developed the back-propagation neural network for predicting cognitive impairment with high discriminative performance (accuracy: 0.91; sensitivity: 93.3%; specificity: 90.0%) for community screening.
OCT analysis of preoperative foveal microstructure in recent-onset macula-off rhegmatogenous retinal detachment: visual acuity prognostic factors (see page 1743)
Pre-operative OCT assessment of macula-off rhegmatogenous retinal detachment indicated the impact of foveal involvement and of subretinal hyper-reflective points as possible markers of inflammation, and as negative predictors of postoperative visual recovery.
Iris freckle: a distinct entity (see page 1749)
Iris freckles are distinct from naevi as they tend to be bilateral, multiple, located centrally, flat, small-sized with irregular margins, confined to anterior stromal layer without any structural secondary effects or tendency for malignant transformation.
Ophthalmic quality of life in the adult Danish population: an epidemiological study (see page 1755)
In the unselected adult population, ophthalmic quality of life (OQoL) correlated positively with visual acuity. OQoL correlated negatively with age below the age of 60 years and correlated positively with age in subjects older than 60 years.
Manhattan vision screening and follow-up study (NYC-sight): a nested cross-sectional assessment of falls risk within a cluster randomised trial (see page 1761)
Increased awareness of falls risk is needed by eye care providers due to the link between falling and vision impairment. This eye health screening study detected a significant amount of falls risk in an underserved population.
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Contributors N/A.
Competing interests None declared.
Provenance and peer review Not commissioned; internally peer reviewed.