The sodium and potassium concentrations and the lactic dehydrogenase (LDH) activity were estimated in the aqueous and serum of five children with retinoblastoma. Two patients who had a high aqueous LDH activity also showed grossly elevated potassium levels in their aqueous. Though the exact reason for this high potassium concentration in the aqueous is not apparent, it seems likely that cell necrosis within the tumour mass was a contributory factor. It is unlikely that aqueous electrolyte estimations in retinoblastoma could prove to be of any diagnostic value.
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