Article Text

Download PDFPDF
Blood rheology and proliferative retinopathy in homozygous sickle cell disease.
  1. B E Serjeant,
  2. K P Mason,
  3. R W Acheson,
  4. G H Maude,
  5. J Stuart and
  6. G R Serjeant


    Some haematological and rheological features were compared in 27 age and sex matched pairs of patients (15 male, 12 female) with homozygous sickle cell (SS) disease with and without proliferative sickle retinopathy (PSR). Significant haematological differences between the groups were a higher haemoglobin and a lower fetal haemoglobin in PSR positive males and a higher MCHC in PSR positive females. The plasma viscosity and characteristics of erythrocyte filterability did not differ between those with and those without PSR, although PSR positive males had a significantly higher whole blood viscosity when measured at high shear and at the patient's own packed cell volume.

    Statistics from

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.