The angiogenic activity of various parts of the retina in kittens with oxygen-induced retinopathy has been studied by the use of a corneal micropocket technique and chorioallantoic assay. The results indicate that in retinopathy of prematurity the most important role in the pathogenesis of fibrovascular proliferation is played by the so-called primary avascular retina, that is, that part of the retina which has not yet been vascularised during ontogenesis.
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