Article Text

Download PDFPDF
Cobalt plaque versus enucleation for uveal melanoma: comparison of survival rates.
  1. K S Adams,
  2. D H Abramson,
  3. R M Ellsworth,
  4. B G Haik,
  5. M Bedford,
  6. S Packer,
  7. J Seddon,
  8. D Albert and
  9. L Polivogianis
  1. Department of Ophthalmology, Manhattan Eye, Ear and Throat Hospital, New York, New York 10021.


    Two hundred and twenty-three patients treated by cobalt plaque for uveal melanoma were compared with 416 patients treated by enucleation for uveal melanoma in terms of patient survival. The median follow-up time for the patients treated by cobalt plaque was 4.3 years. Kaplan-Meier survival curves were calculated up to five years following treatment based on time to tumour-related deaths. Cox's proportional hazards multivariate analysis was performed to determine which variables were related to melanoma-related deaths while controlling for age, size, and location of the tumours. Statistically significant predictive factors were location of tumour and largest tumour dimension. There was not a statistically significant difference in survival between patients treated by cobalt plaque and those treated by enucleation.

    Statistics from

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.