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Ceftriaxone diffusion from blood to aqueous humour in man.
  1. D Gobeaux,
  2. L Ambart,
  3. J L Couderc,
  4. P H Renard,
  5. B De Charnace and
  6. F Lokiec
  1. Department of Anaesthesiology, Fondation Rothschild, Paris, France.


    Ceftriaxone penetrates into the aqueous humour in man. The interaction of indomethacin on the disposition of ceftriaxone appeared to be time-dependent. Indomethacin delayed ceftriaxone penetration into, but enhanced its persistence in, the aqueous humour, permitting a period of antibioprophylaxis covering the required time for surgical treatment.

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