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Corneal subepithelial monoclonal kappa IgG deposits in essential cryoglobulinaemia.
  1. I Kremer,
  2. P Wright,
  3. S Merin,
  4. J Weiss,
  5. A I Pick and
  6. H Kaufman
  1. Department of Ophthalmology, Beilinson Medical Center, Petah Tiqva, Israel.


    A 60-year-old man suffering from photophobia and visual disturbances was found to have bilateral superficial corneal grey-white gelatinous deposits. An abnormal cold-precipitable serum component was found and characterised as homogeneous IgG-kappa immunoglobulin. Corneal immunohistochemical examination revealed subepithelial IgG-kappa deposits, focally replacing Bowman's layer. The patient underwent superficial keratectomy in both eyes with satisfactory visual results.

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