Article Text


Optic nerve hypoplasia in children.
  1. S. M. Zeki and
  2. G. N. Dutton
  1. Tennent Institute of Ophthalmology, Weston Infirmary, Glasgow.


    Optic nerve hypoplasia (ONH) is characterised by a diminished number of optic nerve fibres in the optic nerve(s) and until recently was thought to be rare. It may be associated with a wide range of other congenital abnormalities. Its pathology, clinical features, and the conditions associated with it are reviewed. Neuroendocrine disorders should be actively sought in any infant or child with bilateral ONH. Early recognition of the disorder may in some cases be life saving.

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