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Heterogeneity in dominant anterior segment malformations.
  1. G. E. Holmström,
  2. W. P. Reardon,
  3. M. Baraitser,
  4. J. S. Elston and
  5. D. S. Taylor
  1. Department of Ophthalmology, Hospitals for Sick Children, London.


    Peters' anomaly is usually a sporadic or autosomal recessive condition. We present three families whose members had dominantly inherited anterior segment anomalies with variable expression, including typical Peters' anomaly in at least one family member. Slit-lamp examination of parents and family members of children with Peters' anomaly is therefore important to exclude dominant inheritance.

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