Article Text

Download PDFPDF
Human T lymphotropic virus type 1 uveitis after Graves' disease.
  1. K Yamaguchi,
  2. M Mochizuki,
  3. T Watanabe,
  4. K Yoshimura,
  5. M Shirao,
  6. S Araki,
  7. N Miyata,
  8. S Mori,
  9. T Kiyokawa and
  10. K Takatsuki
  1. Blood Transfusion Service, Kumamoto University Medical School, Japan.

    Abstract

    A distinct clinical entity of uveitis associated with human T lymphotropic virus type 1 (HTLV-I) has been reported previously. During the period between January 1989 and April 1992, 93 patients were observed with HTLV-I uveitis and a significant correlation was found between Graves' disease and HTLV-I uveitis. Sixteen of the 93 patients with HTLV-I uveitis (17.2%) had a previous history of Graves' disease. Fifteen patients were female (15/60, 25.0%) and one was male (1/33, 3.0%). Interestingly, uveitis occurred after the onset of Graves' disease in all cases. On the other hand, none of 222 patients with idiopathic uveitis who were seronegative to HTLV-I had a history of Graves' disease. Although the mechanisms by which HTLV-I causes the correlation between uveitis and Graves' disease are unknown, the present data suggest that immune mediated or autoimmune mechanisms are involved in HTLV-I uveitis.

    Statistics from Altmetric.com

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

    Linked Articles