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Toxic side effects of local anaesthetics on the human cornea.
  1. M Boljka,
  2. G Kolar and
  3. J Vidensek
  1. Department of Ophthalmology, University Ljubljana, Slovenija.


    The cytotoxic effects of 0.5% amethocaine (tetracaine) on the human cornea were investigated by scanning electron microscopy. The ultrastructural examination of epithelial cells showed damage of the cell membrane, rare-faction and loss of microvilli, deposits of amethocaine on the corneal surface and accelerated desquamation of superficial epithelial cells.

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