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Diffuse intraepithelial sebaceous carcinoma of the conjunctiva
  1. KARIN U LOEFFLER
  1. Universitaets-Augenklinik, Killianstrasse 5,
  2. D-79106 Freiburg, Germany
  3. Department of Ophthalmology, University of Illinois,
  4. 1855 W Taylor Street, Chicago IL 60612,
  5. and Department of Ophthalmology,
  6. Loyola University Chicago, 2160 S First Avenue,
  7. Maywood IL 60153, USA
  1. JAY I PERLMAN
  1. Universitaets-Augenklinik, Killianstrasse 5,
  2. D-79106 Freiburg, Germany
  3. Department of Ophthalmology, University of Illinois,
  4. 1855 W Taylor Street, Chicago IL 60612,
  5. and Department of Ophthalmology,
  6. Loyola University Chicago, 2160 S First Avenue,
  7. Maywood IL 60153, USA
  1. Karin U Loeffler, MD, Universitaets-Augenklinik Sigmund-Freud-Strasse 5, D-53105 Bonn, Germany.

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Editor,—Recently, Margo and coworkers1described a case of intraepithelial sebaceous carcinoma of the conjunctiva and eyelid erroneously diagnosed as a unilateral blepharoconjunctivitis for 10 years. This was reported to be the first published case of de novo sebaceous carcinoma in the conjunctival epithelium without evidence of a tumour focus within the eyelid. We present another case of diffuse intraepithelial sebaceous carcinoma of the conjunctiva presenting as blepharoconjunctivitis and superior limbic keratitis of 10 months’ duration.

CASE REPORT

A 70-year-old woman presented with a 10 month history of left sided, unilateral redness, tearing, and swelling of the lids. Examination showed marked conjunctival injection and thickening along the superior temporal and inferotemporal limbus, with moderate lid thickening, and pale corneal changes (Fig 1). There was mild foreshortening and scarring of the inferior fornix. A presumptive diagnosis of carcinoma in situ was considered with a secondary diagnosis of sebaceous gland carcinoma with intraepithelial spread. Biopsies of several sites of limbal, …

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