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Letter to the Editor
Recurrent uveitis in a patient with adult onset cyclic neutropenia associated with increased large granular lymphocytes
  1. ALEJANDRO RODRIGUEZ
  1. Immunology and Uveitis Service, Department of Ophthalmology. Massachusetts Eye and Ear Infirmary, Harvard Medical School. Boston, MA, USA
  2. Division of Rheumatology, Fallon Clinic, Worcester, MA, USA
  3. Division of Ophthalmology, Fallon Clinic, Worcester, MA, USA
  4. Immunology and Uveitis Service, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School. Boston, MA, USA
  1. ROBERT A YOOD
  1. Immunology and Uveitis Service, Department of Ophthalmology. Massachusetts Eye and Ear Infirmary, Harvard Medical School. Boston, MA, USA
  2. Division of Rheumatology, Fallon Clinic, Worcester, MA, USA
  3. Division of Ophthalmology, Fallon Clinic, Worcester, MA, USA
  4. Immunology and Uveitis Service, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School. Boston, MA, USA
  1. THOMAS J CONDON
  1. Immunology and Uveitis Service, Department of Ophthalmology. Massachusetts Eye and Ear Infirmary, Harvard Medical School. Boston, MA, USA
  2. Division of Rheumatology, Fallon Clinic, Worcester, MA, USA
  3. Division of Ophthalmology, Fallon Clinic, Worcester, MA, USA
  4. Immunology and Uveitis Service, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School. Boston, MA, USA
  1. C STEPHEN FOSTER
  1. Immunology and Uveitis Service, Department of Ophthalmology. Massachusetts Eye and Ear Infirmary, Harvard Medical School. Boston, MA, USA
  2. Division of Rheumatology, Fallon Clinic, Worcester, MA, USA
  3. Division of Ophthalmology, Fallon Clinic, Worcester, MA, USA
  4. Immunology and Uveitis Service, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School. Boston, MA, USA
  1. C Stephen Foster, MD, Massachusetts Eye and Ear Infirmary, 243 Charles Street, Boston, MA 02114, USA.

https://doi.org/10.1136/bjo.81.5.415

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    Editor,—A 35-year-old white man was referred with a 1 month history of recurrent bilateral uveitis.

    The patient had a history of cyclic neutropenia beginning at age 19. Severe neutropenia (total neutrophil count as low as 68 cells × 106/l), lasting about 3 days, was documented to occur at the time of clinical symptoms. Prednisone produced a marked diminution in episodes of symptomatic neutropenia.

    At age 35, the patient developed iritis in his left eye during a ‘crisis’. This was treated with 0.1% dexamethasone phosphate solution. The anterior chamber inflammatory reaction subsided, but 1+ cells persisted in the vitreous despite an injection …

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