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Editor,—Disseminated fungal infection is an important cause of morbidity and mortality in immunocompromised patients, often due to candida and aspergillus species. Endogenous endophthalmitis is a recognised complication.1 We present, to our knowledge, the first reported case of endogenous intraocular infection with the emerging pathogen Ochroconis gallopava, acquired following treatment for chronic lymphocytic leukaemia (CLL).
A 69 year old man presented with a 4 day history of painless loss of vision in the left eye after receiving four courses of fludarabine (25 mg/m2 over 5 days) for CLL. Standard infection prophylaxis following myelosuppression included oral fluconazole 50 mg once daily. His neutropenia improved (7.96×109/l) but profound lymphopenia persisted (0.11×109/l).
Visual acuity was right eye 6/6+4 and left eye hand movements. The right eye was normal throughout. Anterior uveitis, hypopyon, lens opacity, and vitritis compromised left funduscopy. A lymphoproliferative or infective aetiology was suspected. Anterior chamber paracentesis …
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