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Do sex and hormonal status influence choroidal circulation?
  1. Marco Centofantia,c,
  2. Stefano Boninia,
  3. Gianluca Mannia,
  4. Cesare Guinetti-Neuschülera,c,
  5. Massimo G Buccia,
  6. Alon Harrisb
  1. aCattedra di Clinica Oculistica, Università di Roma “Tor Vergata”, Fondazione GB Bietti per l'Oftalmologia, Rome, Italy, bDepartment of Ophthalmology, Indiana University, Indianapolis, USA, cAFaR-CRCCS, Divisione Oculistica Ospedale Fatebenefratelli, Isola Tiberina, Rome, Italy
  1. Marco Centofanti, MD, PhD, Via Bolzano 1, 00198 Rome, Italymcentofanti{at}


AIMS To investigate the relation between pulse amplitude (PA), pulsatile ocular blood flow (POBF), and sex and hormonal status.

METHODS Measurements of POBF and PA were obtained by ocular blood flow tonography in 76 healthy subjects: 32 males and 44 females (age range 17–77 years). Females were divided into two age groups: group 1 (premenopausal) 17–42 years, and group 2 (post-menopausal) 55 years old and over. Two groups of age matched males served as controls.

RESULTS Premenopausal females demonstrated a significantly higher rate of POBF and PA than age matched males and post-menopausal females.

CONCLUSION Sex and hormonal status were shown to influence choroidal circulation.

  • ocular blood flow
  • pulse amplitude
  • choroidal circulation
  • sex hormones
  • intraocular pressure

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