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Letter to the Editor
Keratolysis in a patient with pemphigus vulgaris
  1. MASAHIRO SUAMI,
  2. MASARU KATO,
  3. KENRO KOIDE,
  4. YOSHIMASA USAMI,
  5. NORIMASA HATA,
  6. HIROYUKI MACHIDA,
  7. YOSHIHIRO HOTTA
  1. Department of Ophthalmology, Hamamatsu University, School of Medicine, Japan
  2. Department of Dermatology
  1. KENTARO MATSUMOTO,
  2. MASAHIRO TAKIGAWA
  1. Department of Ophthalmology, Hamamatsu University, School of Medicine, Japan
  2. Department of Dermatology
  1. Accepted for publication 16 April 2001

https://doi.org/10.1136/bjo.85.10.1260c

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    Editor,—Pemphigus vulgaris is an autoimmune, blistering disease of the skin and mucous membranes.1 The characteristic ocular finding is conjunctivitis, and corneal involvement is rare.2 3 We present a case with pemphigus vulgaris with severe keratolysis that required a corneal transplantation.

    CASE REPORT

    A 41 year old man had suffered from pemphigus vulgaris for 2 years, and prednisolone 40 mg/day and cyclosporine 300 mg/day had been prescribed. He was admitted to the Hamamatsu University Hospital on 15 March 1999 with an acute exacerbation of the symptoms because of non-compliance with the corticosteroid therapy. He returned on 17 March 1999 because of increased discharge and visual loss in both eyes. His visual acuity was 20/20 right eye and 20/20 left eye, and his intraocular pressure was 24 mm Hg right eye and 20 mm Hg left eye. No remarkable findings were observed …

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