Editor,—Although still uncommon, endogenous fungal endophthalmitis has increased notably owing to widespread use of immunosuppressive therapy, hyperalimentation, and injecting drug use.Candida is the most common causative organism with isolated cases of Aspergillusreported.1 Rhodotorula species are ubiquitous, airborne, asporogenous yeasts recovered from food, air, soil, water, gastrointestinal tracts, and skin.Rhodotorula spp are usually environmental saprophytes; however, they may seldom cause both systemic and ocular infections, especially in immunocompromised patients.2Reported ocular infections include chronic dacryocystitis,3 keratitis,4 chronic postoperative endophthalmitis,5 and corneal lamellar graft infection.6 We report a case of endogenousRhodotorula minuta andCandida albicans endophthalmitis in an injecting drug user.