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Further pathophysiological insights into age related macular degeneration
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Editor,—We read with great interest the excellent editorial by Ciulla,1 which describes pathophysiological paradigms for age related macular degeneration (ARMD) and the development of choroidal neovascular membranes (CNVM). We were particularly pleased to note that Ciulla considered that “whatever the initial stimulus for CNVM formation, it is clear that angiogenic growth factors are ultimately involved.” Furthermore, he observed that primary vascular changes in the choroid may also be responsible.
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