• triamcinolone acetonide
• silicone oil
• intravitreal injection
• pars plana vitrectomy

For decades, corticosteroids have been known to reduce inflammation and, depending on their concentration, to suppress proliferation of cells. Applied either locally or systemically, steroids have consequently been used for treatment of various ocular diseases. Often, however, the intraocular concentrations of cortisone were not sufficiently high, or the systemic side effects were too pronounced, to effectively treat the ocular disorder. Taking into account that the eye comprises only 0.01% of the whole body volume, and considering that for achieving high concentrations of a drug at its site of action it is best to apply it directly into the region of …