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Should we vaccinate for glaucoma surgery?
  1. R R Seemongal-Dass,
  2. T E James
  1. Department of Ophthalmology, Calderdale Royal Hospital, Salterhebble, Halifax HX3 0PW, West Yorkshire, UK
  1. Correspondence to: R R Seemongal-Dass

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Trabeculectomy is the most common non-laser surgical procedure performed for treatment of all forms of glaucoma. It involves the fashioning of a fistula from the anterior chamber of the eye to the subconjunctival space. This allows for extra drainage of aqueous humour to the subconjunctival space. This produces a localised elevation of the conjunctiva in the area of the trabeculectomy called a “filtering bleb.” Antimetabolites may be used intraoperatively and perioperatively to increase the success of glaucoma filtering surgery by their action on wound healing. 5-Fluorouracil or mitomycin C is administered to the scleral flap during the procedure. Postoperatively; subconjunctival injections of 5-fluorouracil may be given. This is known as an augmented trabeculectomy.

Infective endophthalmitis is a recognised complication of glaucoma filtering surgery. It may occur in the early postoperative period or it may happen years after surgery. Another entity, possibly a precursor to endophthalmitis has been described as blebitis.1 Blebitis is an infection of the trabeculectomy bleb without vitreous involvement.

Clinical features of blebitis include pain, photophobia, conjunctival discharge, and severe conjunctival injection centred on an opalescent filtering bleb. A Siedel test may be positive (this indicates aqueous leakage from the bleb) and there may be an anterior chamber reaction. There is no vitritis.2

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