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Glaucoma: squaring the psychophysics and neurobiology
  1. E A Ansari1,
  2. J E Morgan1,2,
  3. R J Snowden3
  1. 1Department of Ophthalmology, University Hospital of Wales, Cardiff, UK
  2. 2Department of Optometry and Vision Sciences, Cardiff University, UK
  3. 3Department of Psychology, Cardiff University, UK
  1. Correspondence to: Mr J E Morgan, Department of Ophthalmology, University Hospital of Wales, Heath Park, Cardiff CF4 4XW, UK; morganje3{at}cardiff.ac.uk

Abstract

Advances in our understanding of the pathophysiology of retinal ganglion cell death in glaucoma are providing important insights into the functional changes occurring in retinal ganglion cells in the early stages of the disease. These exciting new findings may help us develop psychophysical tests to monitor early retinal ganglion cell damage, possibly before neurons are committed to the process of cell death.

  • glaucoma
  • psychophysics
  • cell shrinkage
  • neurobiology
  • HRP, horseradish peroxidase
  • IOP, intraocular pressure
  • LGN, lateral geniculate nucleus
  • OHT, ocular hypertension
  • POAG, primary open angle glaucoma
  • RGC, retinal ganglion cell
  • SAP, standard automated perimetry
  • glaucoma
  • psychophysics
  • cell shrinkage
  • neurobiology
  • HRP, horseradish peroxidase
  • IOP, intraocular pressure
  • LGN, lateral geniculate nucleus
  • OHT, ocular hypertension
  • POAG, primary open angle glaucoma
  • RGC, retinal ganglion cell
  • SAP, standard automated perimetry
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