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The emphasis of treatment for glaucoma has been the reduction of intraocular pressure (IOP) to a safer level, which, in turn, theoretically will prevent further visual loss. It has been assumed that lowering IOP by medical means has no adverse effect, which could negate the beneficial effect of IOP reduction. However, several reports have raised the possibility that some may adversely affect visual function.1,2 In several studies betaxolol and timolol were compared with respect to their effect on IOP reduction and perimetric findings.3–5 Although timolol lowered IOP more effectively, betaxolol was more effective in preserving the visual field.
These findings suggest that IOP reduction is not the only parameter that demands attention. In this study, we attempted …