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Isolated foveal retinoschisis as a cause of visual loss in young females
  1. S A Kabanarou1,2,
  2. G E Holder1,
  3. A C Bird1,2,
  4. A R Webster1,2,
  5. P E Stanga3,
  6. S Vickers4,
  7. B A Harney5
  1. 1Moorfields Eye Hospital, London, UK
  2. 2Institute of Ophthalmology, London, UK
  3. 3St Paul’s Eye Unit, Royal Liverpool University Hospital, UK
  4. 4The Sussex Eye Hospital, Brighton, UK
  5. 5Gloucestershire Hospitals NHS Trust, UK
  1. Correspondence to: Andrew R Webster, MD, Institute of Ophthalmology, Department of Molecular Genetics, 11–43 Bath Street, London EC1V 9EL, UK; andrew.webster{at}ucl.ac.uk

https://doi.org/10.1136/bjo.87.6.801

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    Foveal or macular retinoschisis is an uncommon retinal disorder, usually seen in patients affected with generalised retinal disease such as X linked retinoschisis,1 Goldmann-Favre syndrome,2 and enhanced S-cone syndrome.3 There have been a handful of previous reports of patients exhibiting foveal retinoschisis in whom there appeared to be limited concomitant peripheral retinal disease,4–6 suggesting the existence of a distinct disorder. We report the clinical findings in four female patients presenting with a reduction in central acuity and exhibiting isolated bilateral foveal retinoschisis, and investigations including scanning laser ophthalmoscopy (SLO) autofluorescence imaging, optical coherence tomography (OCT), and electrophysiology.

    Case reports

    Case 1

    A 17 year old girl presented with bilateral reduction in central vision. With refraction (+0.50DS right, +0.25DS left) her visual acuity was 6/18. On examination the only abnormal finding was thickening of the neurosensory retina at the fovea with a radial pattern of striae bilaterally. There …

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