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Is hyaline degeneration of the cornea a precursor of Salzmann’s corneal degeneration?
  1. M Frising1,
  2. S Pitz1,
  3. D Olbert1,
  4. J Kriegsmann2,
  5. W Lisch3
  1. 1Department of Ophthalmology, Johannes Gutenberg-University, Langenbeckstrasse 1, D-55101 Mainz, Germany
  2. 2Institute of Pathology, Moltkestrasse 32, D-54292 Trier, Germany
  3. 3Municipal Hospital Hanau, Leimenstrasse 20, D-63450 Hanau, Germany
  1. Correspondence to: M Frising; frising{at}augen.klinik.uni-mainz.de

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Hyaline degeneration of the cornea has been described by Smolin and Thoft1 as a specific and rare pathological entity. Other authors have used the term hyaline degeneration of the cornea synonymous with climatic droplet keratopathy, or spheroidal degeneration of the cornea.2 A literature search failed to reveal any cases of initially diagnosed hyaline degeneration of the cornea as a precursor of Salzmann’s corneal degeneration. We present the first case known to us of initially diagnosed hyaline degeneration of the cornea, assumed to be a precursor of Salzmann’s corneal degeneration.

Case report

A 34 year old woman was referred to our department in April 1998 with increasing opacity of the left cornea. Her medical and ophthalmological history was uneventful. The lower third of the left cornea showed a slightly elevated, yellowish, subepithelial opacity, sharply demarcated and separated from the limbus by a marked interspace (Fig 1A). The right eye was without pathological findings. The corneal opacity was removed by …

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