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Localised corneal amyloidosis associated with herpetic keratitis
  1. D Tejwani1,
  2. A Azuara-Blanco1,
  3. J MacKenzie2
  1. 1Department of Ophthalmology Aberdeen Royal Infirmary, Grampian University Hospitals, UK
  2. 2Department of Pathology
  1. Correspondence to: Augusto Azuara-Blanco, The Eye Clinic, Aberdeen Royal Infirmary, Aberdeen AB25 2ZN, UK: aazblanco{at}aol.com

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Amyloid diseases are secondary protein structure diseases in which insoluble protein fibrils accumulate extracellularly. Twenty different types of fibrils have been described in human amyloidosis, each with a different clinical picture. Amyloidosis can be generalised, affecting multiple organ systems, or localised and can affect almost any organ of the body. In the eye amyloid is the material commonly seen in lattice corneal dystrophy. Cases of localised corneal amyloidosis have been reported in literature but are quite rare.1–4 We report a case of localised corneal amyloidosis presenting as a large raised gelatinous vascularised lesion in a patient with long standing herpetic keratitis.

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