Purpose: To assess reproducibility of central corneal thickness (CCT) measurement by means of ultrasonic pachymetry.
Methods: Fifty one volunteers underwent three sessions of CCT measurements, each consisting of three CCT measurements, performed by each of three different observers. Intra- and interobserver reproducibility was calculated by means of intraclass correlation coefficient (ICC). The expected range of variability between two independent evaluations was calculated using scatter plots of each test-retest difference against their mean. The standard deviation of the mean differences in the test-retest scores was used to describe the differences in the score spread.
Results: The ICC ranges of the intra- and interobserver evaluations were 0.95–0.97 and 0.89–0.95 respectively; the expected variability was ⩽±1% and ⩽± 2% respectively (95% confidence interval).
Conclusions: The measurement of CCT by means of ultrasonic pachymetry is highly reproducible.
- CCT, central corneal thickness
- ICC, intraclass correlation coefficient
- IOP, intraocular pressure
- OHT, ocular hypertension
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Funded by a grant from the Ministero dell’Universita’ e della Ricerca Scientifica, Italy
None of the authors has any proprietary or commercial interest in the manuscript.
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