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Oral pilocarpine for Sjögren’s syndrome
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Sjögren’s syndrome is an autoimmune disease that affects exocrine glands and causes keratoconjunctivitis sicca. Ocular complications include corneal ulceration, episcleritis, keratitis, and bacterial or viral infection. The use of artificial tears is the mainstay of treatment. It has been suggested that pilocarpine, a cholinergic parasympatheticomimetic …