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Relation between axial length of the eye and hypotensive effect of latanoprost in primary open angle glaucoma
Abstract
Aims: To study the effect of axial length on the hypotensive effect of latanoprost in primary open angle glaucoma (POAG) in a prospective, observational study.
Methods: The authors measured axial length and baseline intraocular pressure (IOP) of 109 eyes with POAG, and then repeated the IOP measurements at 1, 3, and 6 months after starting treatment with latanoprost.
Results: The mean IOP level was significantly lower in eyes with a shorter axial length compared with the eyes with a longer axial length both at 3 and 6 months of treatment (p = 0.03 and p = 0.04, respectively, ANOVA).
Conclusion: The hypotensive effect resulting from treatment with latanoprost could be related to ocular axial length.
- axial length
- glaucoma
- intraocular pressure
- latanoprost
- CACG, chronic angle closure glaucoma
- IOP, intraocular pressure
- LAL, long axial length
- MAL, medium axial length
- MMP, matrix metalloproteinase
- POAG, primary open angle glaucoma
- SAL, short axial length
- axial length
- glaucoma
- intraocular pressure
- latanoprost
- CACG, chronic angle closure glaucoma
- IOP, intraocular pressure
- LAL, long axial length
- MAL, medium axial length
- MMP, matrix metalloproteinase
- POAG, primary open angle glaucoma
- SAL, short axial length