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“Finger-tip” cryotherapy probes: treatment of squamous and melanocytic conjunctival neoplasia
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  1. P T Finger
  1. Correspondence to: Paul T Finger MD, The New York Eye Cancer Center, 115 East 61st Street, New York City, New York, USA; pfingereyecancer.com

Abstract

Aim: To describe the use of a new spatulated cryoprobe in treatment of conjunctival neoplasia.

Methods: A new cryoprobe design was submitted to Mira, Inc resulting in new hand held probes capable of producing homogeneous freezing over large surface areas. The active surface of the small, medium, and large spatulated probes are 8.5 mm2, 25.2 mm2, and 70 mm2. End freezing reduces the possibility of inadvertent freezing of adjacent tissues (outside the targeted zone). In this series, the probes were employed to treat patients with squamous and melanocytic conjunctival neoplasia.

Results: 12 consecutive patients with malignant conjunctival neoplasia were treated with these new cryotherapy probes. Techniques of probe construction and clinical use are described. Cryoburns of the cornea, sclera, and conjunctiva were formed and recorded by digital photography. Ophthalmic examinations before and after surgery demonstrated that no acute intraocular or adnexal complications occurred. No loss of visual acuity could be attributed to this use of the cryoprobes.

Conclusion: “Finger-tip” cryoprobes were used to treat malignant conjunctival neoplasia (squamous and melanocytic). Probe design allowed for uniform freezing over large surface areas. This cryoprobe design appears to be ideal for treatment of conjunctival tumours.

  • CR, cooling rate
  • F/T, freeze-thaw
  • FDA, Food and Drug Administration
  • GMP, Good Manufacturing Practices
  • ISO, International Standards Organisation
  • TT, tissue temperature
  • conjunctiva
  • sclera
  • cryotherapy
  • melanoma
  • squamous carcinoma
  • sebaceous carcinoma
  • cancer
  • CR, cooling rate
  • F/T, freeze-thaw
  • FDA, Food and Drug Administration
  • GMP, Good Manufacturing Practices
  • ISO, International Standards Organisation
  • TT, tissue temperature
  • conjunctiva
  • sclera
  • cryotherapy
  • melanoma
  • squamous carcinoma
  • sebaceous carcinoma
  • cancer

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Footnotes

  • The work is supported by The EyeCare Foundation, Inc and Research to Prevent Blindness, New York, USA.

  • Dr Finger has no proprietary interest in the instrument described in this study.

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