You are here

  • Home
  • Archive
  • Volume 90, Issue 1
  • Prothrombotic and atherosclerotic risk factors lack significance in NAION patients harbouring mitochondrial DNA mutations

Article Text

Article menu
Download PDFPDF
Letter
Prothrombotic and atherosclerotic risk factors lack significance in NAION patients harbouring mitochondrial DNA mutations
  1. K K Abu-Amero1,
  2. T M Bosley2
  1. 1Mitochondrial Research Laboratory, Department of Genetics, King Faisal Specialist Hospital and Research Centre, Riyadh, Kingdom of Saudi Arabia
  2. 2Neuro-ophthalmology Service, King Khaled Eye Specialist Hospital, Riyadh, Kingdom of Saudi Arabia
  1. Correspondence to: Dr Khaled K Abu-Amero Mitochondrial Research Laboratory, Department of Genetics, King Faisal Specialist Hospital and Research Center (MBC # 03), PO Box 3354, Riyadh 11211, Kingdom of Saudi Arabia; kamero{at}kfshrc.edu.sa

https://doi.org/10.1136/bjo.2005.078071

Statistics from Altmetric.com

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

    We recently reported that a group of patients with non-arteritic anterior ischaemic optic neuropathy (NAION) had an increased prevalence of potentially pathological mitochondrial DNA (mtDNA) mutations, implying a link between mitochondrial disease and this optic neuropathy.1 We decided to investigate the association of other risk factors for NAION in these same patients.

    Case reports

    NAION patients were genotyped for the presence of prothrombotic polymorphisms that have been reported in association with NAION,2,3 including factor II G20210A prothrombin variant, factor V Leiden G1691A variant, MTHFR C677T and …

    View Full Text