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Relationship between macular hole size and the potential benefit of internal limiting membrane peeling
  1. R Tadayoni,
  2. A Gaudric,
  3. B Haouchine,
  4. P Massin
  1. Service d’Ophthalmologie, Hôpital Lariboisière, Université Paris 7, Paris, France
  1. Correspondence to: R Tadayoni Service d’Ophtalmologie, Hôpital Lariboisière, 2, Rue Ambroise Paré, 75010 Paris, France;ramin.tadayoni{at}


Aim: To investigate the relationship between the size of macular holes and the possible benefit of internal limiting membrane (ILM) peeling.

Methods: 84 consecutive cases of idiopathic macular hole followed up for at least 3 months were included in this retrospective study. Surgery comprised pars plana vitrectomy, peeling of any epiretinal membrane, 17% C2F6 (hexafluoroethane) gas filling and 10 days of positioning. 36 eyes had ILM peeling. The main outcome measure was the macular hole closure rate checked by optical coherence tomography.

Results: The overall postoperative closure rate was 90.5%. For macular holes ⩾400 μm in diameter, the rate was 100% with ILM peeling versus 73.3% without (p = 0.015). For smaller macular holes, the rates were 100% in both groups. Postoperative gain in visual acuity was not significantly different in eyes with ILM peeling and those without.

Conclusions: ILM peeling does not seem to be useful for macular hole <400 μm in diameter. Its likely benefit has to be investigated for larger macular hole sizes, for which the failure rate is higher.

  • ICG, indocyanine green
  • ILM, internal limiting membrane
  • OCT, optical coherence tomography

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  • Competing interests: None.

  • Published Online First 29 June 2006

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