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Adal-1 bioadhesive for sutureless recession muscle surgery: a clinical trial
  1. M E Mulet1,2,
  2. J L Alió1,2,
  3. M M Mahiques2,
  4. M M Mahiques3,
  5. J M Martín3
  1. 1Ophthalmology Department, Miguel Hernández University, Alicante, Spain
  2. 2Research and Development Department, Vissum Instituto Oftalmologico de Alicante, Spain
  3. 3Biomaterials Department, Alicante University, Alicante, Spain
  1. Correspondence to: Professor Dr Jorge L Alió Vissum-Instituto Oftalmológico de Alicante, Avenida de Denia S/N, Edficio Vissum 03016 Alicante, Spain; rdioa{at}


Aims: To evaluate the efficacy and biotolerance of the Adal-1 adhesive for muscle sealing in strabismus surgery.

Methods: 27 eyes were included in the study: 17 in the control group and 10 in the study group. Surgery was performed on the recession of the horizontal rectus muscles. In the control group the muscle was joined to the sclera by a Vicryl 7/0 suture. In the study group, the Adal-1 adhesive was used instead. The efficacy of the sealing of the muscle to the sclera and the biotolerance of the surrounding tissues were evaluated.

Results: The muscular recession in the control group was 8.17 (SD 2.38) with displacement of the sealing point of 0.02 (1.7) mm. In the group sealed with adhesive, the muscular recession was 9.09 (3.08) and the displacement was 0.15 (1.56) mm, with no significant differences between the techniques (p<0.05). The inflammation of the surrounding tissues in the immediate postoperative period was greater with the suture technique (p>0.05), but there were no differences in the other postoperative periods (Mann-Whitney U test).

Conclusion: Adal-1 was an effective and safe alternative to sutures in muscle recession for strabismus surgery in this study.

  • bioadhesives
  • muscle sealing
  • strabismus surgery

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