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Ocular cicatricial pemphigoid (OCP) is a systemic autoimmune disease of unknown aetiology. It causes a chronic, scarring conjunctivitis and frequently affects other mucous membranes. Definitive diagnosis is made by immunofluorescent staining of conjunctival tissue demonstrating IgG, IgM, and or IgA in the basement membrane.1 Dapsone is an immunomodulating sulphonamide and has widely been used in the treatment of mild to moderate OCP.2–4 All patients treated with dapsone show varying …
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