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Infectious crystalline keratopathy associated with intravitreal and posterior sub-Tenon triamcinolone acetonide injections
  1. D A Hollander,
  2. E L Clay,
  3. Y Sidikaro
  1. Jules Stein Eye Institute, University of California, Los Angeles, CA, USA
  1. Correspondence to: David A Hollander MD, MBA, Cornea, External-Ocular Disease and Uveitis Division, Jules Stein Eye Institute, UCLA, 100 Stein Plaza, Los Angeles, CA 90095, USA; hollander{at}

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Infectious crystalline keratopathy (ICK) is a rare, progressive microbial infection characterised by branching, intrastromal crystalline opacities and minimal ocular inflammation. Predisposing factors most commonly include topical corticosteroids, previous corneal surgery, herpetic keratitis, neurotrophic keratopathy, and topical anaesthetic abuse.1–3 We describe a patient who developed ICK following intravitreal and posterior sub-Tenon (PST) triamcinolone acetonide injections despite being off topical corticosteroids for 6 months.

Case report

A 75 year old man with diabetes mellitus developed cystoid macular oedema (CMO) in the left eye following cataract extraction complicated by anterior vitrectomy, anterior chamber intraocular lens placement (ACIOL) and subsequent ACIOL exchange. The CMO resolved with topical prednisolone acetate 1% and a posterior sub-Tenon injection (PST) of triamcinolone acetonide (40 mg). After being off topical corticosteroids for 6 months, the CMO recurred and …

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  • Supported by the Heed Fellowship Fund (Cleveland, OH) (DAH) and the Vernon O Underwood Family Fellowship Fund (DAH).

  • The authors have no financial interest in any of the material presented in this manuscript.

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