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Integrity of foveal cones in multiple evanescent white dot syndrome assessed with OCT and foveal reflection analyser
  1. M J Kanis,
  2. D van Norren
  1. University Medical Center Utrecht, Heidelberglaan 100, PO Box 85500, AZU E03.136, Utrecht, Netherlands
  1. Correspondence to: MrMartijn J Kanis University Medical Center Utrecht, Heidelberglaan 100, PO Box 85500, AZU E03.136, Utrecht, Netherlands; mkanis{at}

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In this report, foveal photoreceptor involvement in a case of multiple evanescent white dot syndrome (MEWDS) is described by using two optical techniques: optical coherence tomography (OCT) and foveal reflection analysis (FRA). OCT showed a transient disruption of the foveal photoreceptor outer segments. FRA, a recently developed quantitative technique, showed disarray of the foveal cones.

Case report

A 20 year old myopic Sudanese female presented at our hospital with a central visual field defect of her right eye, associated with photopsia. Visual acuity was 0.3; intraocular pressure was 16 mm Hg. Funduscopic examination of the affected eye showed some pigment epithelial alterations in the macular area, with an irregular macular reflex. Upon visual field examination, the affected eye showed a 12 dB decrease in central sensitivity, and a small blind spot enlargement was seen. No such changes were found in the left eye. OCT showed degeneration or disarray of foveal photoreceptor outer segments in the …

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  • Funding: This work is supported by the Dr F P Fischer Foundation. The Dr F P Fischer Foundation had no involvement in the design; in the collection, analysis, and interpretation of data; in the writing of this report; and in the decision to submit this report for publication.

  • Competing interest statement: The authors have no competing interests to declare.