Article Text

Download PDFPDF
Hypertensive iridocyclitis
  1. E C Kim,
  2. T P Margolis
  1. FI Proctor Foundation and Department of Ophthalmology, University of California San Francisco, San Francisco, CA, USA
  1. Correspondence to: Todd P Margolis MD, PhD, Medical Sciences Building, S-310, 513 Parnassus Avenue, Box 0412, University of California San Francisco, San Francisco, CA 94143-0412, USA; todd.margolis{at}

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

A new ocular presentation of cytomegalovirus?

The single most common diagnosis assigned to patients with uveitis is “idiopathic,” and in a recent large epidemiological study 48% of new cases of uveitis were assigned this diagnosis.1 However, with the development of new diagnostic technologies, the discovery of novel ocular pathogens, and the recognition that established ocular pathogens can present in previously unrecognised ways, fewer patients are now being diagnosed with “idiopathic” uveitis. Examples of novel ocular pathogens include Bartonella henselae,2Borrelia burgdorfi,3 West Nile virus,4Tropheryma whippelii,5 microsporidia,6Baylisascaris procyonis,7 and the leptospires.8 Examples of established ocular pathogens that can present in previously unrecognised ways include atypical presentations of toxoplasmosis,9,10 herpesviruses as the cause of the acute retinal necrosis syndrome11,12 and some cases of Posner-Schlossman syndrome,13 and varicella zoster virus as the cause of progressive outer retinal necrosis.14 In addition, two independent groups recently reported evidence linking rubella virus with Fuchs’ heterochromic iridocyclitis.15,16 In the current issue of the BJO (p 852), de Shryver et al present evidence in support of cytomegalovirus (CMV) as a cause of hypertensive iritis in immune competent individuals.17

CMV is an extremely common human pathogen, infecting …

View Full Text


  • Support: National Institutes of Health Grants EY10008 and EY02162 and a Senior Scientific Investigator Award to TPM from Research to Prevent Blindness (New York, NY, USA).

  • The authors have no competing financial interests.

Linked Articles