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Metastatic pleural mesothelioma initially masquerading as chalazion
  1. E K Tsina1,
  2. D Papaioannou2,
  3. F O Matsouka3,
  4. P A Kosmidis3
  1. 1Department of Ophthalmology, Hygeia Hospital, Athens, Greece
  2. 2Histopathology Department, Hygeia Hospital, Athens, Greece
  3. 32nd Medical Oncology Department, Hygeia Hospital, Athens, Greece
  1. Correspondence to: Efthymia K Tsina MD, PhD, Department of Ophthalmology, Hygeia Hospital, 35 Kifisias Street, Athens, 11523, Greece; etsina{at}

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Metastases confined to the eyelid are rare. They usually derive from breast, skin, gastrointestinal, and urogenital tracts.1 Malignant pleural mesothelioma is an uncommon malignancy presenting a steady rise in its incidence over the past 25 years.2 It usually gives local metastases, although distant metastases are also reported.2

To our knowledge, an eyelid metastasis from pleural mesothelioma has never been reported. We describe a patient with pleural mesothelioma who developed a solitary eyelid metastasis. The lesion initially manifested as a recurrent chalazion. Histological confirmation has been obtained antemortem. Histopathology was consistent with the primary tumour.

Case report

A 57 year old man presented with unilateral painful swelling of the left upper eyelid followed by high fever and weight loss. During the previous 6 weeks, he had been treated with local and systemic antibiotics for recurrent chalazia without any improvement. His medical history included pleural malignant …

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  • We do not have any competing interests to declare.