Statistics from Altmetric.com
Neurofibromatosis 1, a common inherited disorder,1 is considered a neurocristopathy characterised by pathological hamartomatous proliferations of neural crest derived tissues.1,2 Neurofibromatosis can be observed in any tissue with neural crest cells throughout the body, including the eye. However, retinal and choroidal lesions had been considered unusual in eyes with this disease,3 although Lisch nodules are frequently observed.4 Because choroidal abnormalities especially have been reported in up to 100% of cases during examinations using infrared monochromatic light and the confocal scanning laser ophthalmoscope (SLO),5 choroidal involvement is thought to be common in neurofibromatous 1.
Conventional optical coherence tomography (OCT) can non-invasively obtain optical cross sectional retinal images with histological detail.6 Newly developed three dimensional (3-D) OCT operates in a so called transverse fashion and yields OCT images originating at the same axis and plane as the retina.7,8 Because this instrument simultaneously produces SLO and interferometric OCT images, it readily allows detection of an area of pathology in …
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.