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Bilateral diffuse uveal melanocytic proliferation (BDUMP) is a rare paraneoplastic syndrome first described by Machemer 40 years ago in a patient with pancreatic carcinoma.1 Gass and associates later expanded the syndrome to include round red patches in the fundus, multifocal areas of retinal pigment epithelial (RPE) atrophy, rapidly progressive cataracts, retinal detachments, and choroidal thickening.2 There have been 34 reported cases since Machemer first described it, and all have had bilateral involvement.3–8 After searching databases such as MEDLINE (1947 to the present), Exerpta Medica/EMBASE (1947 to the present), and Ophthalmic Literature (1947 to 1988) using the key words BDUMP, melanocytic proliferation, paraneoplastic, and uvea, we report the first case—to the best of …
Competing interests: None declared.
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