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Histopathological findings after retinal endovascular lysis in central retinal vein occlusion
  1. Nicolas Feltgen,
  2. Hansjuergen Agostini,
  3. Claudia Auw-Haedrich,
  4. Lutz L Hansen
  1. Department of Ophthalmology, University of Freiburg, Freiburg, Germany
  1. Correspondence to: Dr Nicolas Feltgen Department of Ophthalmology, University of Freiburg, Killianstrasse 5, 79106 Freiburg, Germany; nicolas.feltgen{at}

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Although visual results after use of the new surgical method of retinal endovascular lysis (REVL) seem encouraging,1,2 its effectiveness has not been proved in a controlled, prospective clinical trial. From a histological postmortem study of eyes with central retinal vein occlusion (CRVO), it is still questionable whether an older thrombus can be dissolved using recombinant tissue plasminogen activator (rt-PA).3 We report on the histopathological findings in a human eye 9 months after REVL.

Case report

We report the case of a 62-year-old woman having a 7-week-old, highly ischaemic CRVO in her left eye with hand movement vision. Although we were concerned about treating …

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  • Competing interests: None.

  • The necessary ethics committee approval was secured for this study from the ethics committee of the University of Freiburg, Elsaesser Strasse 2m, Haus 1A, D-79110 Freiburg, Germany.