Aim: To determine the prevalence of preglaucomatous angle-closure disease in central Myanmar.
Methods: A population-based survey of inhabitants ⩾40 years in the Meiktila District was carried out; 2481 subjects were identified, 2076 participated and 2060 underwent gonioscopy of at least one eye. Eyes with angles traditionally described as “occludable” were recorded as primary angle-closure suspects (PACS); eyes with PACS and peripheral anterior synechiae (PAS), or an increased intraocular pressure but without primary angle-closure glaucoma, were recorded as primary angle closure (PAC).
Results: The prevalence of PACS in at least one eye was 5.7% (95% CI 4.72 to 6.62); prevalence increased with age and was more common in women (p<0.001). The prevalence of PAC in at least one eye was 1.50% (95% CI 1.47 to 1.53). All participants with PAS had at least 90° of closure (range 90–360°).
Conclusion: The prevalence of preglaucomatous angle-closure disease (PACS and PAC) in this population was 5.7% and 1.5%, respectively. PACS was more common in women, and its prevalence increased with age.
- GON, glaucomatous optic neuropathy
- IOP, intraocular pressure
- ISGEO, International Society for Geographical and Epidemiological Ophthalmology
- MOH, Meiktila Eye Study
- PAC, primary angle closure
- PACG, primary angle-closure glaucoma
- PACS, primary angle-closure suspects
- PAS, peripheral anterior synechiae
- VDCR, vertical cup:disc ratio
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