We read with interest the article by Mollan et al¹ who have concluded that previous isotretinoin use does not cause a clinically significant reduction in night vision in most people, and that the retinal toxic effects of isotretinoin may be measurable by electroretinography (ERG) and dark adaptation (DA). Although the authors have successfully highlighted the importance of counselling patients for potential irreversible loss of DA following isotretinoin use, their report, in our opinion, has failed to substantiate the need for routine screening of potential military and civilian commercial aviators.

In their study, 2 of 47 patients …