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Topographic optic disc analysis by Heidelberg retinal tomography in ocular Behçet’s disease
  1. Nilufer Berker1,
  2. Ufuk Elgin2,
  3. Pinar Ozdal3,
  4. Aygen Batman2,
  5. Emel Soykan1,
  6. Seyhan S Ozkan3
  1. 1
    Ankara Ulucanlar Eye Research Hospital, Department of Retinal and Uveal Diseases, Ankara, Turkey
  2. 2
    Ankara Ulucanlar Eye Research Hospital, Department of Glaucoma, Ankara, Turkey
  3. 3
    Ankara Ulucanlar Eye Research Hospital, Department of Retinal and Uveal Diseases, Ankara, Turkey
  1. Nilüfer Berker, Huseyinonat Sokak, Sahinbey Ap, 10/6, Asagi Ayranci, 06540, Ankara, Turkey; niluferberker{at}; niluferberker{at}


Aim: To compare the topographic characteristics of the optic discs in patients with severe and mild ocular Behçet’s disease by using Heidelberg retinal tomographaphy (HRT).

Methods: This prospective study included 47 eyes of 47 patients with ocular BD who were being followed-up at the Uveitis Clinic of the Ankara Ulucanlar Eye Research Hospital, Ankara, Turkey. The patients were divided into two groups. Group 1 consisted of 21 eyes with mild uveitis, and group 2 consisted of 26 eyes with severe uveitis. All patients underwent topographic optic disc analysis by HRT II, and the quantitative optic disc parameters of both groups were compared by non-parametric Mann-Whitney U test.

Results: The mean cup volume, rim volume, cup area, disc area and cup depth in group 1 were found to be statistically significantly greater than those in group 2 (p<0.0001, p = 0.03, p = 0.021, p = 0.01 and p = 0.017, respectively), while the difference between the mean cup-to-disc ratios in group 1 and group 2 were found to be statistically insignificant (p = 0.148).

Conclusion: A relationship was found between the severity of ocular BD and optic disc topography determined by HRT. In eyes with smaller optic discs, uveitis was observed to have a more severe course with more frequent relapses than those with larger discs.

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  • Competing interests: None declared.

  • Abbreviations:

    Behçet’s disease


    Heidelberg retinal tomography

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