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A 48-year-old British Caucasian male, presented aged 45 with progressive peripheral and autonomic neuropathy. There was a 2 year history of bilateral veil-like floaters. His mother had died of FAP aged 67 years. Three siblings and two daughters were fit and well.
Cardiovascular and systemic examinations were normal. Neurological assessment revealed symmetrical sensorimotor polyneuropathy, and bilateral carpal tunnel syndrome. Visual …
aNational Amyloidosis Centre, Centre for Amyloidosis & Acute Phase Proteins, Department of Medicine, University College of London, Hampstead Campus, London NW3 2PF, United Kingdom.
bCellular Pathology, The Medical School, University of Birmingham, Birmingham, UK
Competing interests: None declared.
Attribution of work to: Ophthalmology Department, Leicester Royal Infirmary, and National Amyloidosis Centre, London.