More information about text formats
I read with interest the article by Dr. Cohn, et al regarding the
natural history of
autosomal dominant optic atrophy (DOA). The authors describe an average
10-year follow up for 69 patients with genetically confirmed DOA. In
study, 6 (9%) patients enjoyed improvement in visual acuity by 2 or more
I found this surprising, and I wonder if the authors could provide...
I found this surprising, and I wonder if the authors could provide
information regarding this group. Is it the opinion of the authors that
patients actually improved or that this may represent testing artifact or
Were they significantly younger than the rest of the cohort? Was their
significantly shorter? By how much did the acuities improve among this
Was their baseline acuity more likely to come from outside records?
Michael S Lee, MD