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It is often stated that atropine drops should not be used, or are contraindicated, in children with Down syndrome.1 2 Some authors have stated that the mydriatic and cycloplegic effects are overly prolonged,3 whereas others have expressed apprehension regarding potential systemic toxicity.2 4 No evidence exists, however, to support either of these concerns.
It is plausible that previous investigators4 might have believed that the allegedly prolonged cycloplegic effect of atropine in Down syndrome patients could …
Competing interests: None declared.
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