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Aggressive metastasising adenocarcinoma of the retinal pigment epithelium with trisomy 21
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  • Published on:
    Authors' response
    • Ludwig M. Heindl, MD
    • Other Contributors:
      • Gottfried O. H. Naumann, Friedrich E. Kruse, Leonard M. HolbachAgg

    Dear Editors

    We thank Dr Munier and Dr Satgé for their interest in our work on “Aggressive metastasising adenocarcinoma of the retinal pigment epithelium with trisomy 21” [1] and welcome the opportunity to respond to their comments.

    We are in agreement with Dr Munier and Dr Satgé that life-threatening ophthalmic tumours must be kept in mind while taking care of patients with Down syndrome. Despite an imp...

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    Conflict of Interest:
    None declared.
  • Published on:
    Awareness on eye tumours and Down syndrome
    • Francis L Munier, eye cancer specialist
    • Other Contributors:
      • Daniel Satgé, Laboratoire d'Anatomie pathologique, Centre Hospitalier, 19000 Tulle, France

    Dear Editor

    A metastizing adenocarcinoma of the retinal pigment epithelium in a 37-year-old man with Down syndrome (DS) has recently been reported in the British Journal of Ophthalmology [1]. In the article the authors underlined an unusual and atypical aggressive behaviour of the tumour which was the first well documented adenocarcinoma of the retinal pigment epithelium with metastases. Although solid tumours are...

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    Conflict of Interest:
    None declared.