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Giant cavernous haemangioma mimicking a fifth nerve neurofibroma involving the orbit and brain
  1. K Y C Lee1,2,
  2. K S Fong1,
  3. H L Loh3,
  4. M K Heran4,5,
  5. J Rootman1,5,6,7
  1. 1
    Singapore National Eye Centre, Singapore
  2. 2
    Singapore Eye Research Institute, Singapore
  3. 3
    Department of Pathology, Singapore General Hospital, Singapore
  4. 4
    Department of Radiology, University of British Columbia, Canada
  5. 5
    Vancouver General Hospital, Vancouver, British Columbia, Canada
  6. 6
    Department of Ophthalmology and Visual Sciences, University of British Columbia, Canada
  7. 7
    Department of Pathology, University of British Columbia, Canada
  1. K Y C Lee, Singapore National Eye Centre, 11 Third Hospital Avenue, Singapore 168751; mjm_kcl{at}

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We illustrate an unusual case of a giant cranio-orbital cavernous haemangioma that mimicked a fifth nerve neurofibroma. A 54-year-old male presented with a right orbital mass involving the upper lid and sub-brow region producing ptosis, proptosis and globe displacement. Imaging revealed a large intracranial and orbital component with the lesion following the course of the trigeminal nerve. An initial clinical diagnosis of neurofibroma was made. Surgical debulking of the anterior orbital component of the lesion yielded a histology consistent with cavernous haemangioma. Giant cavernous haemangioma with intracranial and intraorbital components may mimic a neurofibroma. Cavernous haemangiomas are vascular malformations consisting of dilated blood vessels separated by fibrous tissue.1 2 Intracranial cavernous haemangiomas extending into the orbit are uncommon. We report a case of a giant cavernous haemangiomas involving the intracranial, extracranial and orbital compartments.

Case report

A 54-year-old male presented with an 11-year history …

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  • Funding: None.

  • Competing interests: None.

  • Ethics approval: Ethics approval was obtained.

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