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Oculoglandular syndrome associated with reactivated Epstein–Barr-virus infection
  1. P Charbel Issa1,
  2. A M Eis-Hübinger2,
  3. K Klatt1,
  4. F G Holz1,
  5. K U Loeffler1
  1. 1
    Department of Ophthalmology, University of Bonn, Bonn, Germany
  2. 2
    Institute of Virology, University of Bonn, Bonn, Germany
  1. Dr P Charbel Issa, Department of Ophthalmology, University of Bonn, Ernst-Abbe-Str 2, 53127 Bonn, Germany; peter.issa{at}

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A 51-year-old woman presented with a 3-week history of a unilateral, right-sided painless swollen upper lid and non-tender preauricular lymphadenopathy (fig 1A). Parinaud oculoglandular syndrome (POS) was diagnosed. Three weeks before, she was treated for a root infection of a tooth in her right upper jaw. She was slightly febrile and was put on Amoxicillin for the last 8 days, but without any improvement of symptoms. The past medical history was remarkable for a history of rheumatoid polyarthritis that was treated with methotrexate (MTX).

Figure 1 (A) Patient with Parinaud oculoglandular syndrome on the right site. (B) Tarsal conjunctiva with follicles and hyperaemia. (C) Granulomatous inflammation with lymphocytes, epithelioid histiocytes and multinucleated giant cells. Patient consent has been obtained for publication of this figure.

Visual acuity was …

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  • Competing interests: None.

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